The game opens with Peter Parker explaining how he became Spider-Man, and the creation of the Venom symbiote. Additionally, players may choose to collect hidden power-ups to gain more web fluid capacity or gain moves and abilities for both Spider-Man and Venom. This version includes a limited supply of Spider-Man’s web fluid, which can be refilled by picking up special markers scattered throughout levels or dropped by enemies. In addition to the two main characters, the game features three additional bosses: Shocker, Silver Sable, and Carnage.

Both Spider-Man and Venom are playable, and each has his own series of levels. The Game Boy Advance version of Ultimate Spider-Man is a side-scroller beat ’em up, divided into seven “issues”, each containing three chapters. The Windows version is a port of the PlayStation 2 and Xbox versions, developed by Beenox. The PlayStation 2 and Xbox versions were developed by Treyarch and are drastically different from the handheld versions, which were developed by Vicarious Visions. The game was published by Activision for the PlayStation 2, Xbox, Microsoft Windows, Game Boy Advance, GameCube and Nintendo DS in September 2005.

Ultimate Spider-Man is a 2005 action-adventure video game based on the Marvel Comics character Spider-Man and the comic book of the same name.

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